The #1 Nurse Practitioner Exam Review & CNE Resource

Med-Challenger NP


Med-Challenger NP is the highest quality, easiest to use, and most-trusted nurse practitioner exam review question bank and knowledge improvement suite for NP knowledge review, ANCC & AANP FNP-BC Initial Certification exams, and annual ANCC & AANP maintenance of certification “contact hour” and pharmacotherapy CE requirement compliance. Med-Challenger’s nurse practitioner review course is 100% pass-guaranteed and provides over 2400 case-based Q&A following the American Association of Nurse Practitioners and American Nurses Credentialing Center exam blueprints, media banks, and ongoing content updates.

What’s more, with 216 ANCC “contact hour” CNEs built-in including 45 Pharmacotherapy CEs, Med-Challenger’s NP exam review Qbank gives nurse practitioners everything needed to ace NP exams and fulfill “contact hour” CNE requirements year after year with less time, labor, and worry.

Join the nurse practitioners who’ve used Med-Challenger to outperform on exams – and protect their practice. Try it for free today.

Useful year after year for Exams, MOC & CE requirements.
With Med-Challenger, it’s well in hand.

This is the BEST way to maintain one’s medical knowledge, unequivocally!! Chris Curran
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Nurse Practitioner Board Review, Med-Challenger NP, Complete Review, Ongoing Updates, CNE Credits

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Pass NP exams, guaranteed.

Earn ANCC “contact hour” CNEs too.

See why Med-Challenger NP is the #1 Nurse Practitioner Exam Review in addition to having the MOST Q&A and HIGHEST pass-rate.

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    Time-saving adaptive learning engine leaves nothing behind

    Time-saving adaptive learning engine prioritizes missed and yet-to-be-seen content so you get every ounce of value from your review purchase.

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    Automatic prescriptive remediation takes you where you need to go next

    Automatic prescriptive remediation guidance offers “deeper dives” to repair your weak areas of knowledge.

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    Adaptive, AANP blueprint-based exam simulation

    Simulate the board examination instantly, while taking Q&A in the right subject areas and in the right amounts, everytime.

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    Practice, Review & Assessment modes for enhanced retention

    Work the way you want. No pressure practice mode, read-friendly Review mode, and CE credit assessments

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    Create your own custom exams!

    Create your own exams with our Custom Exam Builder. Save your custom exams and re-use them for study or routine self-assessment.

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    Earn CNE "contact hours" including annual Pharmacotherapy CEs

    Earn CNE “contact hours” within assets quickly. Manage credit claims and produce CNE certificates.

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    Dashboards, analytics & reports keep things on track

    Track your progress and scores, compare against global averages, maximize your purchases, and maximize your time.

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    Daily content updates & new Q&A, plus peer-to-peer fun

    With your Med-Challenger account, you can play our weekly Quick Quiz game with new content and peer leaderboards

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    Work anywhere, anytime, on any device - in less time

    Work on any device from anywhere. 100% responsive design and time-saving adaptive tools.

Proven NP Exam Success

After 25 years in exam review, we know how to get results – and fast.

Exam Pass-rate
Avg. Score Improvement
Avg. Study Time Saved

Included Content & Questions

For Med-Challenger NP Nurse Practitioner Exam Review Qbank

Over 0
Topics Covered
Over 0
AANP-style Questions

Nurse Practitioner Question Topics

AANP and ANCC publish content blueprints of the material that will appear on their respective exams.

This is how we determine which material appears in your adaptive Qbank.

Eyes, Ears, Nose, and Throat7%
Neurologic System6%
Infectious Diseases3%

Family Nurse Practitioner

There are two certification options, both of which are addressed by Med-Challenger NP:

American Academy of Nurse Practitioners (AANP) is a board examination. Upon passing, the credentials awarded are FNP-C (C-denotes certified)

  • Questions: 150 questions (135 are scored; 15 are pretest and not scored) 
  • Exam Breakdown
    • Assessment (~36%)
    • Diagnosis (~24%)
    • Plan (~23%)
    • Evaluation (~17%)
  • Exam Breakdown by Patient Age:
    • Prenatal (~3%)
    • Pediatric (including newborn and infant (~14%)
    • Adolescent (early/late) (~18%)
    • Adult (~37%)
    • Geriatric (~21%)
    • Frail Elderly (~7) 

American Nurses Credentialing Center (ANCC) is a board examination. Upon passing, the credentials awarded are FNP-BC (-BC denotes board certified)

  • Questions: 200 (175 are scored; 25 are pretest and are not scored)
  • Exam Breakdown
    • Foundations for Advanced Practice (~37%)
    • Professional Practice (~17%)
    • Independent Practice (~46%)

High-Yield NP Questions

AANP-style, blueprint-based Q&A.
Just like you’ll see on the actual AANP exam.

Positively-stated, Case-based Question Stems

No “negatively phrased” questions, no “A and B”…you know what we mean. Our questions always address important “key point” blueprint-based content in a well structured manner.

A 45-year-old man presented to you 3 months ago with leg weakness and ataxia. You performed a physical examination, which revealed clonus and hyperreflexia. Magnetic resonance imaging (MRI) of his spine is shown in Figure 1; MRI of the brain performed at the same time was normal.

Figure 1

Today, the patient is presenting to you with complaints of fatigue, blurry vision, and incontinence. Repeat MRI of the brain is shown below (see Figure 2)

Figure 2

A diagnosis of multiple sclerosis (MS) can be made based on fulfilling which of the following criteria?

Clear Answer Options

A question’s difficulty is defined by the choice of distractors. Good distractors determine the difficulty level of a question. Therefore, good distractors are one of the most important features of a high quality question.

radiographic evidence of a single lesion occurring ≥ 2 times
radiographic evidence of ≥ 2 lesions occurring simultaneously in time
radiographic evidence of ≥ 2 lesions occurring ≥ 2 times
radiographic evidence of multiple brain lesions regardless of time of occurrence
radiographic evidence of spinal cord lesion with clinically consistent symptoms regardless of time of occurrence

High-yield Remediation

Understanding why an answer choice is incorrect is just as important as knowing why it is correct. Med-Challenger questions contain detailed explanations for the correct and incorrect answer choices along with integrated media for those that learn best by visual stimuli.


No definitive diagnostic laboratory test exists for MS, but MRI of the brain can be extremely useful and should be performed in all patients when MS is in the differential diagnosis.

More than 95% of patients with clinically definite MS have an abnormal result on a brain MRI. Specific findings on MRI can provide evidence of disease disseminated in time and space (different parts of the brain or spine). MS plaques typically appear as high-signal (white) areas on T2-weighted images. Features of lesion seen on MRI suggestive of MS include an elliptical shape, discrete borders, lack of mass effect, and gadolinium enhancement. Typical locations include the periventricular area (as seen on the brain MRI), the corpus callosum, the cerebellar peduncles, the brain stem, the juxtacortical area, and the dorsolateral spinal cord (as noted on the MRI of his spine).


Ferri FF. Multiple sclerosis. In: Ferri FF. Ferri’s Clinical Advisor. 2015:785-787.

Calabresi PA, Multiple sclerosis and demyelinating conditions of the central nervous system. In: Goldman-Cecil Medicine. 2016; 411: 2471-2480.

Table of Contents

Everything you need to know for NP exams and current NP practice.

Bowel and Bladder Function
Common Issues in the Elderly
Neurological Issues in the Elderly
Physical Impairment in the Elderly
Other Primary Geriatrics
Anticipatory Guidance
Childhood Immunizations
Development Milestones
Disease Prevention
Failure to Thrive
Female Pubertal Development
Gynecologic Health Care
Male Pubertal Development
Normal Growth
Periodic Health Examination/Screening
Pregnancy and Contraception
Self-Identity and Family Influence
Sexuality and Emotional Development
Sexually Transmitted Infections (incl. pharmacology)
Acute Complications of Pregnancy
Breast Disorders
Chronic Medical Illness During Pregnancy
Diseases of the Vulva & Vagina
Family Planning and Reproductive Health
General Approach to the Pregnant Patient
Menopause: Management, Risks, & Benefits of Therapy
Menstrual Disorders
Ovarian Disorders
Screening and Regular Health Care in Adult Women
Sexual Assault
Sexually Transmitted Infections: Female
Uterine Disorders
Cardiac Arrest and Therapeutic Hypothermia
Cardiac Issues in the ICU
Critical Care Pharmacology
Endocrine Issues in the ICU
Ethical Dilemmas in the ICU
Gastroenterology in the ICU
General Care Issues in the ICU
Hematologic Issues in the ICU
Hemodynamic Monitoring
Infectious Disease Issues in the ICU
Management of Severe Obstructive Lung Disease
Neurology Issues in the ICU
Obstetrical Critical Care
Renal Issues in the ICU
Respiratory Failure
Surgical Critical Care Issues in the ICU
Thromboembolic Disease
End-of-Life Issues
Ethical-Legal Issues – Consent, Error Disclosure, Physician Impairment
Interpersonal/Adaptive Skills – Diversity, Crisis, Special Needs
Maintenance of Medical/Clinical Skills
Operational Logistics – Laws, Error Prevention, Improvement Process
Cancer Prevention and Screening
Diet and Prevention
Exercise and Prevention
Prevention of Cardiovascular Disease
Prevention of Infectious Disease
Congenital Heart Disease in the Adult
Dysrhythmias/Conduction Defects
Endocarditis and Other Cardiovascular Infections
Ischemic Heart Disease
Myocardial Disease
Pericardial Disease
Valvular Heart Disease
Vascular Disease
Pediatric Cardiovascular Disorders
Evaluation and Management of Pulmonary Disorders
Interstitial, Inflammatory, & Parenchymal Lung Diseases
Obstructive Airway Disease
Pulmonary Vascular Disease
Sleep Medicine
Allergic Complications of Transfusions
Auto-Immune Systemic Disorders
Drug Allergy
Food Allergy
Primary Immunodeficiency Disorders
Rhinitis, Sinusitis, & Conjunctivitis
Skin Disorders
Urticaria and Angioedema
Pediatric Allergy and Immunology
AIDS and HIV Infection
Bacteremia, Sepsis Syndrome, & Fever of Unknown Origin
Bacterial Infections
Enteric Infections
Infections of Joints and Bones
Lower Respiratory Tract Infections
Nosocomial/Procedure & Device-Associated Infections
Parasitic Infections
Sexually Transmitted Diseases and Infections of Reproductive Organs
Systemic Fungal Infections
Tick-Borne Illnesses
Upper Respiratory Tract Infections
Viral Infections
Pediatric Infectious Diseases
Diseases of the Cornea
Diseases of the Ear
Diseases of the Oral Cavity, Pharynx, and Salivary Glands
Disorders of the Nose and Paranasal Sinuses
Eye Infections & Other Ophthalmologic Disorders
Retinal Disease
Pediatric Eye, Ear, Nose, and Throat Disorders
Dermatitis (Eczemas)
Dermatologic Immunology
Disorders of Hair & Nails
Nodules and Tumors of the Skin
Papulosquamous Dermatoses
Photosensitivity Dermatoses
Pigment Disorders
Skin and Soft Tissue Infections
Vascular Dermatoses
Vesiculobullous Dermatoses
Pediatric Dermatology
Adrenal Disorders
Anterior Pituitary Disorders
Diabetes Mellitus
Disorders of Calcium Metabolism and Bone
Hypoglycemia Not Due to Insulinoma
Hypothalamic Disorders
Lipid Disorders
Nutritional Disorders
Polyglandular Disorders
Posterior Pituitary and Water Metabolism
Thyroid Disorders
Pediatric Endocrine Disorders
Inflammatory Disorders of Joints – Immunologic
Inflammatory Disorders of Joints – Non-Immunologic
Non-Inflammatory Musculoskeletal Disorders
Pediatric Rheumatology and Musculoskeletal Disorders
Acute Renal Failure
Chronic Kidney Disease
Glomerular Disorders
Other Urology
Prostate Disorders
Tubulointerstitial Disease
Urinary Tract Infections
Water and Electrolyte Balance
Pediatric Nephrology and Urology
Biliary Tract Disease
Colonic and Anorectal Disease
Esophageal Disease
Liver Disease
Pancreatic Disease
Small Intestinal Disease
Stomach or Duodenum
Undiagnosed Gastrointestinal Hemorrhage
Pediatric Gastrointestinal Disorders
Coagulation Factor Disorders and Thrombotic Disorders
Genetic Disorders of Hemoglobin
Hematologic Malignancies
Hemolytic Anemia
Hypoproliferative Anemia
Platelet Disorders
Transfusions & Bone Marrow Transplantation
Pediatric Hematology and Oncology
Bone Tumors
Breast Cancer
Cancer Prevention, Screening, & Survivorship
Complications of Cancer and its Treatment
Endocrine Tumors and Endocrine Manifestations of Tumors
Gastrointestinal or Hepatic Cancer
Gynecologic Cancer
Lung Cancer
Neoplasms of the Head and Neck
Oncologic Emergencies
Urologic Cancer
Penile Disorders
Sexually Transmitted Infections: Male
Testicular Disorders
Addiction Medicine
Anxiety Disorders
Eating Disorders
Factitious Disorders
Mood Disorders
Personality Disorders
Schizophrenia and Delusional (Paranoid) Disorders
Somatoform Disorders
Pediatric Psychiatric Disorders
Central Nervous System Infections
Cerebrovascular Disease
Cranial Neuropathy
Diseases of Muscle and Neuromuscular Function
Disorders of Cerebral Function
Movement Disorders
Multiple Sclerosis and Other Demyelinating Diseases
Nerve Root Syndromes/Mechanical Lesions of the Spine
Peripheral Neuropathy
Pediatric Neurologic Disorders

Written and Maintained by Experts

Continually Updated
All content is continually maintained by clinical expert peer-review.


Mary Alice O’Brien, DNP, APRN, FNP-BC
Associate Professor
Georgetown University School of Nursing
Washington, DC

Built-in CE Credit Resources

Earn CE credits while you study. Knock out requirements fast.

Earn Up To
ANCC ''contact hour'' CNE Credits

Earn up to
ANCC Pharmacotherapy contact hours

CNE Accreditation

The Postgraduate Institute for Medicine is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center‘s Commission on Accreditation. This educational activity for 216 contact hour(s) is provided by the Postgraduate Institute for Medicine. Designated for 45.7 contact hours of pharmacotherapy credit for Advance Practice Registered Nurses.

Earn and Claim Credits in a snap.

  • Score 80% or better on topic-based CNE assessments
  • ANCC CNE "contact hour" earnings will appear in your CME Claims Center
  • Produce PDF CNE Certificates (claim credits) instantly
  • PDFs list all topics claimed for hassle-free submission
  • Return anytime to reprint or review historical earnings
Earn and Claim Credits Easily, Earn CME Credits, AMA PRA Category 1 CME Credits


Challenger is a medical education firm that truly does it all. Their NP products are of outstanding quality and effectiveness!D. Miller
Med-Challenger’s NP course is hands down one of the best investments I have ever made. Easy to use and I can do everything from one screen.
I passed my exam with ease.K. Hicks

You don’t just get the best content.
You get the best tools too.

Great content does nothing on it’s own. You have to use it.
We give you the most tools to “get it done” – your way.

All Features & Benefits


Other “QBanks” stop short.
With Med-Challenger, you not only get the largest NP QBank – you get a complete system of self-assessment, knowledge upkeep, and career MOC efficiency that serves you now and forever.

Med-Challenger's unique objective based user interface

Better than the best “QBank.”

Built for the NP exams – and everything beyond.

We give you over 2400 NP exam review questions with detailed explanations – more than any NP Exam Review Question Bank.

But we also give you additional review tools, content assets, media banks, and time-saving career conveniences – like satisfying MOC requirements on-demand – useful every year.

Our NP exam review doesn’t just get you through exams, it keeps an eye toward your future, your ongoing practice needs, and your quality of life.

In fact, you can add multiple products to your single Med-Challenger account to cover every special need your specific practice career requires.

Searchable clinical media banks

And you’ll never have to re-buy assets ever again!

Instead of wasting time and money every year, we have a better plan -
One-time purchasing and a single low cost Premium Membership super-renewal!
Purchase products at regular price ONCE. Add items at any time. (You'll never pay full price again!)
Get a FULL YEAR of use with every purchase. Then, simply RENEW your Premium Membership when the time comes.
Only $199 / year renews access to ALL of your purchased Med-Challenger assets for another full year of use.
We keep everything current and ready at all times, even adding new materials to annual MOC subscription products.
No more re-buys! No more worries. Enjoy everything you need, on-demand, every year - for less.

With Med-Challenger, you can do everything your NP career requires, more easily, now and forever.

Package Options

Do the boards. Or just do it all.

Buy assets individually or by bundle.

Bundles include multiple assets for “entire career” coverage.
Compare the options below. Start a free trial.

Option 1

NP Basic

Everything for NP Exams & MOC

Med-Challenger NP Exam Review Course + ANCC “contact hour” CNEs + Pharmacotherapy CEs
Nurse Practitioner Basics, Med-Challenger NP, Complete Review, Ongoing Updates, CNE Credits
One Time Purchase*

Asset included:

  • Nurse Practitioner Comprehensive Review
  • Adaptive Qbank with 2400+ AANP-style questions
  • Exam simulation with guided remediation
  • 216 ANCC “contact hour” CNEs
  • 45 Pharmacotherapy Contact Hours
  • Money-back, pass guarantee

Benefits included:

  • One year of access (Premium Membership) free with purchase
  • One-time Purchase! Purchased assets remain in your account forever – No more re-buys!
  • Renew access to ALL PURCHASED ACCOUNT ASSETS for only $199/yr
  • Content updates and annual subscription product additions FREE with active Premium Membership
  • Time-saving adaptive learning engine prioritizes missed and yet-to-be-seen content
  • Automatic prescriptive remediation guidance targets weak areas
  • Ready-made blueprint-based exams
  • Create your own custom exams!
  • Find and earn CME credits within assets quickly
  • Easy CME certificate production
  • Dashboards
  • Analytics & Reports
  • Free weekly Quick Quiz game with new content and peer leaderboards
  • Fully responsive for use on all devices
  • Free customer support

72 hour free trial available

Start Free Full Trial
Add NP Review to Cart


The Library

Everything, Ever

The Med-Challenger Library Subscription: All Courses & All New Additions
Library, Med-Challenger Library Subscription, Every Specialty, Annual MOC, Exam Review, Ongoing Updates, CME Credits, Special CME's, New Products
One Time Purchase*

Assets included:

  • Emergency Medicine
  • Family Medicine
  • Internal Medicine
  • Pediatric Medicine
  • Pediatric Emergency
  • OB/GYN
  • Urgent Care
  • Special Purpose
  • Physician Assistant
  • Nurse Practitioner: Primary
  • Nurse Practitioner: Emergency
  • RN / NCLEX
  • EM LLSA Subscription
  • FM MC-FP KSA Subscription
  • PEDS MOC Part 2
  • Auscultation (Cardio & Pulm)
  • Dermatology
  • Ultrasound
  • ECG Interpretation
  • Radiology Interpretation
  • Risk Management & Malpractice
  • Self-Defense
  • State-required CME
  • Cardiac Center CME
  • Stroke Center CME
  • Trauma Center CME

  • AMA PRA Cat. 1 Credits™ and other CME types included
  • New Med-Challenger course assets including new titles and editions FREE as they are released.

Benefits included:

  • One year of access (Premium Membership) free with purchase
  • One-time Purchase! Purchased assets remain in your account forever – No more re-buys!
  • Renew access to ALL PURCHASED ACCOUNT ASSETS for only $199/yr
  • Content updates and annual subscription product additions FREE with active Premium Membership
  • Time-saving adaptive learning engine prioritizes missed and yet-to-be-seen content
  • Automatic prescriptive remediation guidance targets weak areas
  • Ready-made blueprint-based exams
  • Create your own custom exams!
  • Find and earn CME credits within assets quickly
  • Easy CME certificate production
  • Dashboards
  • Analytics & Reports
  • Free weekly Quick Quiz game with new content and peer leaderboards
  • Fully responsive for use on all devices
  • Free customer support

72 hour free trial available

Start Free Full Trial
Add The Library to Cart

How It Works

Your account. Your assets. Your abilities.

Med-Challenger works for both practicing clinicians, clinician educators, and quality directors by providing a singularly efficient and effective system of knowledge review, exam prep, and recurring career requirement fulfillment adaptable to any learning environment or objective.

How it Works
  • Connector.

    1. Create your account

    A single account to hold your assets. Get one free.

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    2. Add assets

    One-time purchase your exam review and MOC requirements.

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    3. Get it done – your way.

    The abilities – the adaptive tools, career utilities, and benefits.

And by the way….
Med-Challenger also works for NP Group Education.

Add group education resources and education management controls to your NP training program or clinical NP group.