The #1 ENP Emergency Nurse Practitioner Exam Review

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Med-Challenger Emergency Nurse Practitioner Exam Review

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Up-to-date ENP Board Review Questions
3600+ ENP Questions
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Detailed Explanations & Rationales
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Included in all product packages:
Intelligent board exam simulators
Topic-based review options
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Practice & review tutor modes
Custom exam builder
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“Med-Challenger’s Emergency NP course is hands down one of the best investments I have ever made. Easy to use and I can do everything from one screen.
I passed my exam with ease.”K. Hicks

Multiple Benefits, Uses & Utilities

Ace Emergency Nurse Practitioner Exam Review with the #1 Online ENP Review Course.
100% Pass-guaranteed ENP Review with ANCC & AAENP MOC “contact hours” and pharmacotherapy CEs too!

  • Everything you need to know.
    • ANCC & AAENP blueprint & ENP Model-based content
    • Written & peer-reviewed by medical specialists
    • AAENP/ANCC-style case-based questions
    • Detailed answers and explanations
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    • Clinical texts and media banks
    • Continually updated
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  • everything you need to know
  • Risk-free, time-saving exam review.
    • 100% pass-guaranteed ENP exam review
    • Adaptive learning intelligent assessment
    • Targets weak areas for total prep in less time
    • Instant feedback & guided remediation
    • Exam simulation & topic-based study options
    • Practice & review tutor modes
    • Custom exam builder
    • 99.8% pass-rate
  • Med-Challenger ENP exam review course
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    • Earn ANCC “contact hour” CNEs
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Content & Questions

Med-Challenger offers the most exam-focused content and review questions.

Over 3600

Blueprint-based Exam Simulation

AAENP and AANP publishe a content blueprint of the material that will appear on the exam.

This is how we determine which material appears in exam simulations.

Eyes, Ears, Nose, and Throat7%
Neurologic System6%
Infectious Diseases3%

Emergency Nurse Practitioner

Developed by the American Academy of Nurse Practitioners Certification Board (AANPCB) in collaboration with the American Academy of Emergency Nurse Practitioners (AAENP).

The following eligibility requirements established by AAENPCB include:

Option 1

  • Minimum of 2,000 direct, emergency care clinical practice hours as a Family NP in the past 5 years.
  • Evidence of 100 hrs of continuing emergency care education
  • Minimum of 30 continuing emergency care education hours in emergency care procedural skills within those 5 yrs.

Option 2

  • Completion of an academic emergency care graduate/post-graduate NP program from an accredited nursing program, or
  • Completion of a dual FNP/ENP graduate/post-graduate certificate program from an accredited nursing program.

Option 3

  • Completion of an approved emergency fellowship program.

Med-Challenger ENP, Emergency Nurse Practitioner (ENP-C) Question Bank, was created specifically to help you receive your ENP-C designation.

  • Over 3600 Questions and Comprehensive Explanations
  • Designed with the AANPCB Examination Blueprint for Emergency Care
  • Receive 100 Continuing Education Credits

Table of Contents

Everything you need to know for ENP exams and current ENP practice.

Abdominal Pain
Acute Pelvic Pain in Women
Acute Vaginal Bleeding
Back Pain
Chest Pain
Depressed Consciousness and Coma
Dizziness and Vertigo
Fever in the Adult Patient
Gastrointestinal Bleeding
Headache: Initial Approach
Nausea and Vomiting
Seizures: Initial Approach
Anorectal Disorders
Colitis, Ileitis, and Functional Bowel Disorders
Esophageal Disorders and Foreign Bodies
Foodborne and Waterborne Diseases
Gallbladder and Biliary Tract Disorders
Liver: Infectious Disorders
Liver: Noninfectious Disorders
Obstruction, Ischemia, Perforation, Peritonitis
Pediatric Gastrointestinal Disorders
Stomach and Duodenal Disorders
Acute Coronary Syndromes – Diagnosis and Challenges
Non-ST-Elevation Acute Coronary Syndromes – Initial Workup
Non-ST-Elevation Acute Coronary Syndromes – Medical Therapies
Non-ST-Elevation Acute Coronary Syndromes – Surgical Invasive Management
Non-ST-Elevation Acute Coronary Syndromes – Special Patient Groups
ST-Elevation Acute Coronary Syndromes – Initial Medical Care
ST-Elevation Acute Coronary Syndromes – Reperfusion Strategies
ST-Elevation Acute Coronary Syndromes – Stabilization of Complications
Cardiac Failure
Cardiac Valve Disorders
Circulation: Aortic Aneurysms
Circulation: Aortic Dissection
Circulation: Hypertension – Emergency Management
Circulation: Peripheral Vascular Emergencies
Dysrhythmia: Basic Concepts
Dysrhythmia: Conduction Disorders
Dysrhythmia: Implantable Devices
Dysrhythmia: Pharmacology
Dysrhythmia: Supraventricular
Dysrhythmia: Ventricular
Endocarditis and Myocarditis
Pericarditis/Pericardial Tamponade (Non-Traumatic)
Cancers of the Skin
Cutaneous Infections
Dermatitis (non-infectious)
Maculopapular Lesions
Papular / Nodular Lesions
Ulcerative Lesions
Vesicular / Bullous Lesions
Basic Science Review: Acid-Base Regulation
Basic Science Review: Regulation of Water and Osmolarity
Clinical Context: Acid-Base Disorders
Clinical Context: Alcoholic and Lactic Acidosis
Clinical Context: Osmol and Anion Gaps
Electrolyte Disorders: Calcium, Magnesium, Phosphorus
Electrolyte Disorders: Potassium
Electrolyte Disorders: Sodium, Chloride
Endocrine Disorders: Adrenal Glands
Endocrine Disorders: Diabetic Ketoacidosis
Endocrine Disorders: Hyperosmolar Hyperglycemic State
Endocrine Disorders: Hypoglycemia
Endocrine Disorders: Thyroid Gland
Miscellaneous: Alcohol-Related Disease
Eye: Assessment
Eye: Glaucoma
Eye: Inflammation and Infection
Eye: Pharmacology
Eye: Vascular Disorders
Nose: Infection and Inflammation
Oral Cavity: Medical Disorders
Otologic Infections
Otologic Signs, Symptoms, Presentations
Throat and Soft Tissue Neck: Medical Disorders
Electrical and Lightning Injuries
Heat-Related Illnesses
High Altitude Disorder
Hypothermia: Accidental
Scuba Diving and Dysbarism
Venomous Animal Injuries: Arthropods
Venomous Animal Injuries: Marine
Venomous Animal Injuries: Reptiles
Disorders of Hemostasis: Factor Deficiencies
Disorders of Hemostasis: Platelets / Fibrinogen
Red and White Blood Cell Disorders
Selected Oncologic Emergencies
Collagen Vascular / Immune Complex Disorders
Hypersensitivity Reactions
The Immunocompromised / Solid-Organ Transplant Patient
Bacterial Infections: Diphtheria, Pertussis, Tetanus
Bacterial Infections: Meningococcemia, Pneumococcemia
Bacterial Infections: MRSA, VRE, ESBL
Bacterial Infections: Pediatric I, II
Bacterial Infections:Tuberculosis
Parasitic Infections
Sepsis Syndromes
Tick-Borne Illnesses
Viral Infections: Hantavirus
Viral Infections: HIV
Viral Infections: Influenza, Mononucleosis, Herpes
Viral Infections: Pediatrics
Viral Infections: Rabies
Air Medical Transport
Disaster Preparedness
Disasters / Terrorism: Biological
Disasters / Terrorism: Chemical
Disasters / Terrorism: Explosives
Disasters / Terrorism: Radiation (incl. Nuclear)
EMS: Overview and Ground Transport
Evidence-Based Medicine
Guidelines in Emergency Medicine
Health Records and Health Information Technology
Interpreting Medical Literature
Medical Error Prevention
Medical Ethics
Medical Law
Occupational Health in the Emergency Department
Risk Prevention
Wellness, Stress, and the Impaired Physician
Bone and Joint Infections
Deep Soft Tissue Infections
Disorders of Muscles
Disorders of the Spine
Overuse Syndromes (incl. Tendinopathy and Bursitis)
Neurological Assessment I, II
Central Nervous System Disorders: Delirium and Dementia
Central Nervous System Disorders: Demyelinating / Inflammatory
Central Nervous System Disorders: Diseases of Movement Control
Central Nervous System Disorders: Seizures
Central Nervous System Disorders: Spinal Cord Syndromes
Central Nervous System Infections
Stroke: Epidemiology and Presentation
Stroke: Initial Work-up
Stroke: Treatment
Headache: Cervical Neck Vessels, Subarachnoid, and Venous Emergencies
Headache: Cluster, Migraine, and Tension
Headache: Less Common Etiologies
Pediatric Nervous System Disorders I, II
Peripheral Nervous System Disorders: Neuromuscular Junction Disease
Peripheral Nervous System Disorders: Neuropathies
Selected Cranial Nerve Disorders
Gynecological Infections: Genital Lesions
Gynecological Infections: Vaginal Discharge
Pregnancy: Labor, Delivery and Their Complications
Pregnancy: Acute Medical, Surgical Complications
Pregnancy: Acute Obstetric Complications
Pregnancy: General Approach to the Pregnant Patient
Pregnancy: Pre-existing Medical Illness
Emergency Psychiatric Evaluation
Schizophrenia / Psychotic Disorders
Somatic Symptom Disorders
Violence, Abuse, Neglect: Assault (incl. sexual)
Violence, Abuse, Neglect: Elderly Citizens
Urological Assessment
Male Genital Problems: Noninfectious
Nephrology, Contrast Induced
Renal Failure: Acute
Renal Failure: Chronic
Renal Transplantation
Sexually Transmitted Infections: Male
Urinary Retention
Urinary Tract Infection
Acute Upper Airway Disorders (Incl. Peds)
Disorders of Pleura, Mediastinum, and Chest Wall
Obstructive/Restrictive Diseases: Fibrosis/Emphysema/Exposure (Incl. Peds) I, II
Obstructive / Restrictive Diseases: Reactive Lower Airway Disorders (Incl. Peds)
Pulmonary Embolism / Hypertension / Edema
Pulmonary Infections (Incl. Peds)
General Approach to the Poisoned Patient
Caustic Ingestion
Cocaine and Other Sympathomimetics Toxicity
Acetaminophen Toxicity
Antibiotics Toxicity and Side Effects
Anticholinergics Toxicity
Antidepressants Toxicity (inc. Serotonin Syndrome)
Antipsychotics Toxicity
Aspirin and NSAIDs Toxicity
Bronchodilator Toxicity
Cardiovascular Drug Toxicity
Hallucinogen Toxicity
Heavy Metal Toxicity
Hydrocarbon Toxicity
Inhaled Toxins
Lithium Toxicity
Opiate Toxicity
Pesticide Toxicity (incl. Organophosphates)
Sedatives and Hypnotics Toxicity (incl. Barbiturates, Benzodiazepines)
Toxic Alcohols
Toxic Plant Ingestion (incl. Mushrooms)
Bites – Mammals (incl. Humans)
Burns: Chemical
Burns: Thermal
EENT Trauma: Eye
EENT Trauma: Nose
EENT Trauma: Oral-Dental
EENT Trauma: Otologic
Orthopedic Injuries: Ankle
Orthopedic Injuries: Cervical Spine
Orthopedic Injuries: Femur and Hip
Orthopedic Injuries: Foot
Orthopedic Injuries: Hand
Orthopedic Injuries: Humerus and Elbow
Orthopedic Injuries: Knee and Lower Leg
Orthopedic Injuries: Shoulder
Orthopedic Injuries: Wrist and Forearm
Special Populations: Geriatric Trauma
Special Populations: Trauma in Pregnancy
Trauma: Abdominal
Trauma: Assessment and Stabilization
Trauma: Face
Trauma: Foreign Bodies
Trauma: Genitourinary
Trauma: Head
Trauma: Multiple and Blast Injuries
Trauma: Pelvic
Trauma: Peripheral Vascular Injury
Trauma: Soft Tissue Neck
Trauma: Spinal Cord
Trauma: Thoracic – Cardiovascular Injuries
Trauma: Thoracic – Chest Wall
Trauma: Thoracic – Esophageal Injuries
Trauma: Thoracic – Pulmonary Injuries
Airway: Adult
Airway: Pediatric
Breathing: Ventilatory Support (Adult / Pediatric)
Monitoring the Emergency Patient
Resuscitation: Adult Cardiac
Resuscitation: Brain (After Cardiac Arrest)
Resuscitation: Neonatal
Resuscitation: Pediatric
Resuscitation: Shock
Resuscitation: Trauma
Procedural Sedation: Adult
Procedural Sedation: Pediatric
Wound Management: General
Wound Management: Closure Techniques
Wound Management: Escharotomy
Wound Management: Incision and Drainage
Wound Management: Nail Trephination
Geriatrics: The Elder Patient: Acute Care
Clinical Decision-making
End of Life Care
Fundamentals of Culturally Competent Care
Psychosocial Crises Intervention
The Combative Patient
The Developmentally and Physically Disabled Patient
The Difficult Patient

Expert Contributors

Written & continually maintained by certified, practicing emergency nurse practitioners.

Continually Updated
All content is continually maintained by clinical expert peer-review.


Andrea C. Eberly, MD, M.S., FAAEM

Contributing Editors / Clinical Reviewers:

Kimberly Collins, MD
Emergency Physician
MedExpress Urgent Care
Tampa, FL

Joseph Scott Savage, DO, FAAEM, FACHE, FSCP, FAIHQ
Staff Physician
Emergency Dept.
Yale-New Haven Health System
Bridgeport Hospital
New Haven, CT

ENP Exam Review Question Samples

Sample ENP Questions from our Question of the Week blog.

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Earn Up To

Earn up to

CME Accreditation

The Postgraduate Institute for Medicine is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center‘s Commission on Accreditation. This educational activity for 267 contact hour(s) is provided by the Postgraduate Institute for Medicine. Designated for 70.4 contact hours of pharmacotherapy credit for Advance Practice Registered Nurses.

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I’d be lost with Med-Challenger’s ENP course. It saves me tons of time, tons of stress, and tons of money! So happy I found this resource.R. Spade, ENP

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Why is Med-Challenger ENP the
Best Emergency Nurse Practitioner Exam Review?

Our Emergency Nurse Practitioner exam review follows the ANCC & AAENP Model and the exam content outline for the American Association of Emergency Nurse Practitioners (AAENP) and American Nurses Credentialing Center (ANCC) Examination. Proven effective for ENP knowledge review, ANCC & AAENP Initial Certification exams, and annual ANCC & AAENP Maintenance of Certification “contact hours” and pharmacotherapy CE requirement compliance, our ENP exam review follows the exam content outline for the American Association of Emergency Nurse Practitioners (AAENP) and American Nurses Credentialing Center (ANCC) Examination and ENP Model giving you more than 3600 emergency nurse practitioner exam review practice questions with detailed explanations peer-reviewed by practicing ENP educators.

Intelligent, time-saving adaptive learning and prescriptive remediation produces the best review in the shortest time. Dashboards, custom exams, and other career-minded MOC utilities are also included. Our proven Emergency Nurse Practitioner exam review (99.8% pass-rate) follows the ENP Model and the exam content outline for the American Association of Emergency Nurse Practitioners (AAENP) and American Nurses Credentialing Center (ANCC) Examination.

What’s more, with 267 ANCC “contact hour” CNEs built-in including 70 Pharmacotherapy CEs, Med-Challenger’s ENP exam review Qbank, gives emergency nurse practitioners everything needed to ace ENP exams and fulfill MOC requirements year after year with less time, labor, and worry.

Med-Challenger’s Emergency Nurse Practitioner Exam Review offers the best ENP review options. Join the many emergency nurse practitioners who’ve used Med-Challenger to outperform on exams – and protect their practice. Try it for free today.

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